SYNTHETIC CALCITONIN

Brand Name & Strength

Miacalcic 50 IU/ml & 100 IU/ml

Reconstitution

Not required

Further Dilution

IV infusion

Dilute dose of 5 – 10 IU/kg in 500 ml diluent

Diluent

NS

Administration & Infusion rate

SC, IM or IV Route of administration is based on indications and volume of medications Prevention of osteoporosis, Paget’s disease and chronic hypercalcaemic states  To be administered via SC or IM injection  If medication volume ≤ 2 ml, it is preferable to administer via SC  If medication volume > 2 ml, it is preferable to administer via IM at varying sites of injection Emergency treatment for hypercalcaemic crisis  To be administered via

IV infusion

over at least 6 hours/day; or  To be administered via slow IV injection in 2 – 4 divided doses

Storage & Stability

RT

(<25 oC)

Fridge

(2 – 8 oC)

After Reconstitution

- -

After dilution

- -

Remarks

One IU corresponds to about 0.2mcg of synthetic salmon calcitonin Allow to reach room temperature before administration The ampoules are for single use only. Leftover solution must be discarded -